「旭茉JESSICA Run」自2007年開始舉辦，作為主辦單位的《旭茉JESSICA》及「旭茉JESSICA慈善基金」希望透過健康的跑步活動，增加香港人對身心健康的關注。此外亦希望藉著慈善跑為社會福利機構籌款，幫助社會上有需要之人士，多年來已累積超過八千名善心讀者報名參加。「旭茉JESSICA Run」所籌得之善款將全數撥捐至「旭茉JESSICA慈善基金」、「青年成就香港部」、「保護遺棄動物協會」及其他受惠機構。
比賽設立多個不同的組別，包括精英挑戰賽、個人挑戰賽和幼兒挑戰賽外、團體挑戰賽、狗狗挑戰賽、南華傳媒盃、學校挑戰賽及旭茉JESSICA x Little Twin Stars挑戰賽，同時大會更會安排嘉年華會及活動給到場人士參與，而多個社會福利機構亦於會場設有攤位活動，介紹機構服務，加深大眾對其之認識 。
"旭茉JESSICA Run" is a charity run event organized by 《JESSICA》 and "JESSICA Foundation" since 2007. We aimed to bring family members together through this charity run, as well as to raise funds for those need help from the society. Over the past years, more than 8,000 enthusiastic runners and family members participated. All funds raised were donated to "JESSICA Foundation", “Junior Achievement Hong Kong" , “Society for Abandoned Animals" and other beneficiaries to support their activities
Different race categories were set up, including Elite Challenge, Individual Challenge, Kids Challenge, Corporate Team Challenge, Dogs Challenge, South China Media Challenge, School Team Challenge, and JESSICA x Little Twin Stars Challenge; we have also arranged fun-filled carnival with different kinds of game booths and clowns for all participants and charity booths from beneficiaries.